Bier verlaagt de ziekte van Parkinson onder mannen

Research Question:
Drinking alcohol reduces the chance of getting Parkinson's?

Study Design:
This overview article contained 32 items with 677550 participants, of which 9994 people with Parkinson's disease.

Results and conclusions:
The researchers found that after having corrected for smoking, a high alcohol consumption compared to a low, the chance of getting Parkinson's disease significantly with 22% [RR = 0.78, 95% CI = 0.67-0.92] reduced.

The researchers found that after having corrected for smoking, a high alcohol consumption compared to a low, the chance of getting Parkinson's disease in prospective cohort studies significantly with 14% [RR = 0.86, 95% CI = 0.75-0.995] reduced.

The researchers found that after having corrected for smoking, a high alcohol consumption compared to a low, the chance of getting Parkinson's disease in matched case-control studies significantly with 26% [RR = 0.74, 95% CI = 0.58-0.96] reduced. Significant is, there is a link at a 95% reliability.

The researchers found a significant Association for beer in the sensitivity analyses [RR = 0.59, 95% CI = 0.39-0.90], but not for wine or liqueur and among men [RR = 0.65, 95% CI = 0.47-0.90] but not among women. Significant because RR of 1 was not in 95% CI of 0.47 to 0.90. RR of 1 is, there is no risk.

The researchers found that every glass of alcohol a day, the odds of getting Parkinson's disease with non-significant 5% RR = 0.95, 95% CI = 0.89-1.02, p for non-linear = 0.85] reduced.

On the basis of the found results the researchers concluded that drinking alcohol, especially beer the chance of getting Parkinson's disease, especially among men decreased. 

Original title:
Alcohol intake and risk of Parkinson's disease: A meta-analysis of observational studies by Zhang D, Jiang H and Xie J.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/24590499

Additional information about El Mondo:
Find here more studies on alcohol.