Voedingsadvies El MondoResearch Question:
Low glycemic index (GI) diet is beneficial in the management of hyperglycemia (high blood glucose levels). Cardiovascular disease is the leading cause of death among diabetics and this is why it is important to the understanding of GI effects on blood lipids. The goal of this systematic litertuuronderzoek of Rcts was therefore to have a low GI Diet on blood lipids to investigate.
A low GI diet can lower cholesterol levels?
Study Design:
This overview article contained 28 Rcts. The random effect was used to treat low with a high GI Diet over at least 4 weeks to compare with each other. This overview article knew 1272 participants while individual studies ranged between 6 to 155 participants.
Results and conclusions:
The researchers found that compared to high GI Diet low GI Diet significantly lowered total cholesterol with-0.13 mmol/l [95% CI =-0.22 to-0.04, p = 0.004, 27 studies, 1441 participants]. Significant is, it can be said with 95% reliability that a low GI Diet really reduced total cholesterol.
The researchers found that compared to high GI Diet low GI Diet reduced LDL cholesterol significantly with-0.16 mmol/l [95% CI =-0.24 to-0.08, p 0.0001, 23 studies, 1281 participants]. Significant because the p-value was less than 0.05.
The subgroup analyses suggested that lowering the LDL-cholesterol levels was greatest in studies with the shortest treatment duration and the largest GI-reduction. In addition, improvements in blood lipids seemed the biggest and the most reliable when the low GI-intervention coupled with an increase in dietary fiber.
When removing the Panel of the studies without adequate randomization, the statistical significance lost, but the average decrease of 0.10 mmol/l remained in both cases.
The meta-analysis showed no effect on HDL-cholesterol levels and triglyceride levels see.
The researchers concluded that a low GI Diet the total-and LDL-cholesterol levels lowered but it had no effect on HDL-cholesterol or triglyceride levels.
Original title:
Low glycaemic index diets and blood lipids: A systematic review and meta-analysis of randomized controlled trials by the LM, Goff Cowland, [...], Frost GS.
Link:
http://www.sciencedirect.com/science/article/pii/S0939475312001524
Additional information about El Mondo:
A high LDL-cholesterol levels and a high triglyceride levels increase the chances of getting heart disease while a high HDL-cholesterol levels the chance of getting heart disease lowers.
A low GI Diet is a diet with a GI number 55 or lower or a power supply with a minimum of 1.5 grams of fiber per 100 kcal.