Luteïne en zeaxanthine via voeding verlagen gevorderde AMD

Research Question:
It is assumed that lutein and zeaxanthin reduce the incidence of age-related macular degeneration (AMD), but the findings are inconsistent. Therefore, a systematic literature review and meta-analysis on the relationship between the intake of lutein and zeaxanthin and the risk of getting AMD.

Lutein and zeaxanthin intake lowers the risk of getting AMD?

Study Design:
This overview article contained 6 cohort studies with
0.12 million participants, of which 2477 people with AMD. The study size ranged between 1709 and 71494 participants. 
The study duration ranged between 5 and 18 years.

Results and conclusions:
The researchers found that people who ate lots of lutein and zeaxanthin non-significant 4% [RR = 0.96, 95% CI = 0.78-1.17] less likely walked on getting ADM than people who ate little lutein and zeaxanthin. Non-significant to say that it is not with 95% reliability can be said that the reduced risk of 4% was due to eating lutein and zeaxanthin.

The researchers found that people who ate lots of lutein and zeaxanthin significant 26% [RR = 0.74, 95% CI = 0.57-0.97] less likely walked on getting advanced AMD than people who ate little lutein and zeaxanthin. Significant with 95% reliability means that it can be said that the reduced risk of 26% was due to eating lutein and zeaxanthin.

The researchers found that people who ate lots of lutein and zeaxanthin significant 38% [RR = 0.68, 95% CI = 0.51-0.92] less likely walked on getting neovascular AMD than people who ate little lutein and zeaxanthin. In other words, there is a significant relationship.

The researchers concluded that eating lutein and zeaxanthin protect against getting advanced AMD but not against getting AMD.

Original title:
Lutein and zeaxanthin intake and the risk of age-related macular degeneration: a systematic review and meta-analysis by Le M, Hong-Liang D, [...], Xiao-Ming L.

Link:

http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8479176

Additional information about El Mondo:
Lutein and zeaxanthin are carotenoids. Read more about carotenoids in the presentation carotenoids.


The levels of lutein and zeaxanthin in a product can be looked up in the NEVO-table.