Selenium verlaagt de kans op het krijgen van prostaatkanker

Research Question:
Prostate cancer is a growing public health problem. Several human studies have demonstrated a potential protective effect of selenium, but the conclusions of the published studies are inconsistent. It was therefore carried out this review article.

Selenium lowers the risk of getting prostate cancer?

Study Design:
This overview article contained 12 studies with participants, of which 13254 5007 people with prostate cancer.

Results and conclusions:
The researchers found that the risk of getting prostate cancer declined with increasing plasma/serum selenium concentration to 170 ng/mL.

Three high qualitative studies included in this meta-analysis showed that the concentration of selenium in toenails (0.85-0.94 ug/g) the risk of getting prostate cancer significantly with 71% reduced [RR = estimated 0.29, 95% CI = 0.14-0.61].  

The researchers concluded that there is a relationship between a relatively narrow range of selenium status and the reduced risk of getting prostate cancer existed. Further studies in populations with low selenium status is needed.

Original title:
Selenium and prostate cancer: systematic review and meta-analysis by Hurst R, Hooper L, [...], Fairweather-Tait SJ.

Link:
http://ajcn.nutrition.org/content/96/1/111.short

Additional information about El Mondo:
Of selenium is known to be the margin between too little and too much selenium is relatively small. That makes swallowing too much selenium selenium is not harmless since the limit is easily exceeded.
Read more about selenium selenium in the presentation.