Voedingsadvies El MondoResearch Question:
Vitamin B6-a high blood value lowers the chances of getting colon cancer?
Study Design:
This overview article contained 8 prospective cohort studies and 1 nested case-control study between 2002 and 2009 with 6064 participants. These 9 studies examined the dietary intake of vitamin B6.
4 nested case-control studies with 883 cases and 1424 controls between 2005 and 2009. These 4 studies examined the blood value of vitamin B6.
There was no publication bias.
Results and conclusions:
The researchers found that the highest intake of vitamin B6 through diet compared with the lowest intake, the chances of getting colon cancer non-significant with 10% [95% CI = 0.75-1.07, there was heterogeneity between the studies] reduced. Non-significant is, there is no link to a 95% reliability.
The researchers found that the highest vitamin B6-blood value (150 picomol/mL) compared with the lowest blood value (12.7 picomol/mL), the chances of getting colon cancer significantly with 48% [95% CI = 0.38-0.71, there was no heterogeneity between the studies] reduced. Significant is, there is a link at a 95% reliability.
The researchers found that every increase in blood value with 100 picomol/mL (= 2 times the standard deviation) the chances of getting colon cancer significantly with 49% [95% CI = 0.3-0.69] reduced.
The researchers concluded that high vitamin B6-blood value the chance of getting colon cancer reduced.
Original title:
Vitamin B6 and Risk or Colorectal lung CancerA Meta-analysis of Prospective Studies by Larsson SC, Orsini N and Cloud A.
Link:
http://www.ncbi.nlm.nih.gov/pubmed/20233826
Additional information about El Mondo:
Both vitamin B6 through diet and through nutritional supplements can increase the vitamin B6-blood value. Read more about vitamin B6.