Nutritional Advice El MondoObjectives:
What are the risk factors and laboratory abnormalities of COVID-19?
Study design:
This review article included 43 studies involving 3,600 patients.
Results and conclusions:
The investigators found among COVID-19 patients, fever [83.3%, 95% CI = 78.4 to 87.7], cough [60.3%, 95% CI = 54.2 to 66.3] and fatigue [38.0%, 95% CI = 29.8 to 46.5] were the most common clinical symptoms.
The investigators found among COVID-19 patients, the most common laboratory abnormalities were elevated C-reactive protein [68.6%, 95% CI = 58.2 to 78.2], decreased lymphocyte count [57.4%, 95% CI = 44.8 to 69.5] and increased lactate dehydrogenase [51.6%, 95% CI = 31.4 to 71.6].
The investigators found among COVID-19 patients, ground-glass opacities [80.0%, 95% CI = 67.3 to 90.4] and bilateral pneumonia [73.2%, 95% CI = 63.4 to 82.1] were the most frequently reported findings on computed tomography.
The investigators found among COVID-19 patients, the overall estimated proportion of severe cases and case-fatality rate (CFR) was 25.6% [95% CI = 17.4 to 34.9] and 3.6% [95% CI = 1.1 to 7.2], respectively.
CFR and laboratory abnormalities were higher in severe cases, patients from Wuhan and older patients, but CFR did not differ by gender.
The investigators concluded the majority of COVID-19 cases are symptomatic with a moderate case-fatality rate (CFR). Patients living in Wuhan, older patients and those with medical comorbidities tend to have more severe clinical symptoms and higher case-fatality rate.
Original title:
Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) in China: A Systematic Review and Meta-Analysis by Fu L, Wang B, [...], Zou H.
Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7151416/
Additional information of El Mondo:
Find more information/studies on coronavirus right here.