Nutritional Advice El MondoObjectives:
The role of hydroxychloroquine (HCQ) in the treatment of COVID-19 is not fully known. Therefore, this review article has been conducted.
Does hydroxychloroquine increase risk of coronavirus disease 2019 (COVID-19)?
Study design:
This review article included 3 studies (n = 474).
Results and conclusions:
The investigators found meta-analysis of 3 studies (n = 210) on viral clearance assessed by RT-PCR showed no benefit [RR = 1.05, 95% CI = 0.79 to 1.38, p = 0.74, I2 = 61.7%, p = 0.07].
The investigators found meta-analysis of 3 studies (n = 474) showed a significant 117% increase in death with hydroxychloroquine, compared to the control [RR = 2.17, 95% = 1.32 to 3.57, p = 0.002, I2 = 0.0%, p = 0.43].
The investigators concluded no benefit on viral clearance is found but there is a significant increase in mortality with hydroxychloroquine compared to control in patients with COVID-19.
Original title:
"Hydroxychloroquine in Patients With COVID-19: A Systematic Review and Meta-Analysis." by Singh AK, Singh A, […], Misra A.
Link:
https://pubmed.ncbi.nlm.nih.gov/32417708
Additional information of El Mondo:
Find more information/studies on coronavirus right here.