First-trimester use of artemisinin derivatives is not associated with an increased risk of miscarriage or stillbirth compared to quinine

Objectives:
Artemisinin combination therapies (ACTs), the most efficacious antimalarials available, are the recommended first-line treatment for Plasmodium falciparum malaria except in the first trimester of pregnancy. Animal embryotoxicity data and the scarcity of safety data in human pregnancies, have prevented artemisinin derivatives from being recommended for malaria treatment in the first trimester except in lifesaving circumstances. Therefore, this review article (meta-analysis) has been conducted.

1 serving/week poultry intake reduces risk of stroke among US people

Objectives:
Does poultry intake reduce risk of stroke?

Study design:
This review article included 7 prospective cohort studies involving 354,718 participants.

Results and conclusions:
The investigators found for the highest versus lowest categories of poultry intake a non-significantly reduced risk of 8% for total stroke [pooled RR = 0.92, 95% CI = 0.82-1.03, I2 = 19.8%, p = 0.28].

Aerobic exercise benefits global cognition in mild cognitive impairment patients

Objectives:
Individuals with mild cognitive impairment (MCI) are at high risk for developing dementia. Physical exercise is a promising intervention for cognitive decline. Systematic reviews regarding the effects of physical exercise on cognitive and psychological outcomes among MCI patients are limited and a systematic review exploring the effects of exercise modalities on the results has not been conducted. Therefore, this review article has been conducted.

Do individuals with mild cognitive impairment benefit from physical exercise?

Vegetable and fruit consumption reduce metabolic syndrome

Objectives:
Does vegetable and/or fruit consumption reduce metabolic syndrome (MetS)?

Study design:
This review article included 20 cross-sectional studies, 1 case-control study and 5 cohort studies.

Results and conclusions:
The investigators found in 16 studies when comparing the highest versus the lowest category of vegetable consumption a significantly reduced risk of 11% [overall multivariable-adjusted RR = 0.89, 95% CI = 0.85-0.93, p 0.001] for metabolic syndrome.

Point-of-use fortification of foods with micronutrient powders containing iron gives a small increase in haemoglobin concentration in preschool children

Objectives:
In 2016, the World Health Organization (WHO) recommended point-of-use fortification of complementary foods with iron-containing micronutrient powders to improve iron status and reduce anaemia in children at risk of anaemia. This recommendation continues to be debated. Therefore, this review article (meta-analysis) has been conducted.

Does point-of-use fortification of foods with iron-containing micronutrient powders reduce anaemia in children at risk of anaemia?

Olive oil consumption decreases LDL cholesterol and triglyceride less than other plant oils

Objectives:
What are the effects of olive oil consumption compared with other plant oils on blood lipids?

Study design:
This review article included 27 RCTs, comprising 1,089 participantes.

Results and conclusions:
The investigators found compared to other plant oils, HDL cholesterol levels (good cholesterol) increased significantly more for olive oil consumption [WMD = 1.37 mg/dL, 95% CI = 0.4 to 2.36].