Voedingsadvies El MondoResearch Question:
Many epidemiological studies have the relationship between the intake of folic acid, the folic acid blood levels and the risk of getting breast cancer examined. However, the findings were inconsistent between the studies. It was therefore carried out this review article.
High folic acid consumption lowers the chance of getting breast cancer?
Study Design:
This overview article contained 16 prospective studies with participants whose 26205 744068 patients with breast cancer and 26 case-control studies with 21820 16826 breast cancer patients and controls (those without breast cancer).
Results and conclusions:
The researchers found in a pooled analysis of all the studies together, a potential non-linear relationship between eating folic acid and getting breast cancer.
The researchers found in prospective studies a U-shaped relationship between eating folic acid and getting breast cancer, with a significantly reduced risk between 153 and 400 micrograms of folic acid per day.
The researchers found in case-control studies a significant negative relationship between eating folic acid and getting breast cancer, with a reduced risk at a high folic acid consumption on breast cancer among women with a high alcohol consumption but not among women with a low alcohol consumption.
The researchers found participants in 8 studies with no significant association between folic acid 5924, bloedwaarden and getting breast cancer.
The researchers concluded that eating folic acid (153 and 400 micrograms of folic acid per day) the chance of getting breast cancer, especially among women with high alcohol consumption reduced.
Original title:
Higher dietary folate intake reduces the breast cancer risk: a systematic review and meta-analysis by Chen P, Li C, [...], Wang h.
Link:
http://www.nature.com/bjc/journal/v110/n9/full/bjc2014155a.html
Additional information about El Mondo:
Find here more studies on folic acid.