Voeding en gezondheid

Veel vitamine C via voeding verlaagt staar

Research Question:
Or vitamin C a protective factor for age-related cataract is, remains unclear. It was therefore carried out this review article.

Vitamin C lowers the chances of getting age-related cataract (cataracts)?

Study Design:
This overview article contained 20 studies on vitamin C intake and 10 studies on serum ascorbaatgehalte (= the vitamin C content in the body). 

Results and conclusions:
The researchers found a high vitamin C intake compared to a low, a significantly reduced risk of 18.6% [RR = 0.814, 95% CI = 0.578-0.231] for age-related cataract. This significantly reduced risk was found in both America and Asia.

The researchers found a high serum ascorbaatgehalte compared to a layer, a significantly reduced risk of 29.6% [RR = 0.564-0704, 95% CI = 0.879] for age-related cataract. This significantly reduced risk was both in nuclear cataract Subcapsular cataract as found.

The researchers concluded that both high vitamin C intake as a high serum ascorbaatgehalte, reduced the chance of getting age-related cataract.

Original title:
Association of vitamin C with the risk of age-related cataract: a meta-analysis by Wei L, Liang G, [...], Lv J.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/25735187

Additional information about El Mondo:
Find here more studies vitamin C.
A vitamin C-rich meal contains at least 100 mg of vitamin c. These meals are rich in vitamin C.

Vegetarisch dieet leidt tot gewichtsverlies

Research Question:
Vegetarian diets can promote weight loss, however the evidence is ambiguous. It was therefore carried out this review article.

Following a vegetarian diet leads to weight loss?

Study Design:
This overview article contained 12 Rcts with a total of 1151 people that a vegetarian diet with an average maturity of 18 weeks.

Results and conclusions:
The researchers found that people who followed a vegetarian diet lost significantly more weight than those who do not vegetarian diet followed [weighted average difference =-2.02 kg, 95% CI =-2.80 to-1.23].

The researchers found in the subgroup analysis (to get more information) that the weight loss in a vegan diet significantly 2.52 kg [95% CI = 3.02-to-1.98] but at a lacto-ovo diet not significant 1.48 kg [95% CI =-3.99 to 0.47] amounted to.

The researchers found in the subgroup analysis that people who followed a vegetarian diet with energy restriction lost significantly more weight than those followed a vegetarian diet without energy restriction [2.21 kg, 95% CI =-3.31 to-1.12 versus 1.66 kg, 95% CI =-2.85 to-0.59]. 

The researchers found in the subgroup analysis that following a vegetarian diet of less than 1 year led to more weight loss than following a vegetarian diet longer than 1 year [-2.05 kg, 95% CI =-2.85 to-1.25 versus-1.13 kg, 95% CI =-2.04 to-0.21].

The researchers concluded that following a vegetarian diet with an average maturity of 18 weeks to a weight loss of 2.02 kg. Most weight loss was achieved with a vegan diet with energy restriction.

Original title:
Vegetarian Diets and Weight Reduction: a Meta-Analysis of Randomized Controlled Trials by Huang RY, Huang CC, [...], Chavarro you.

Link:
http://onlinelibrary.wiley.com/doi/10.1111/obr.12067/abstract

Additional information about El Mondo:
Read here about being overweight.
Read more about vegetarian diet.
Only a vegetarian diet leads to weight loss and return of the diet in addition also low fat and high fiber.

A vegetarian is generally defined as someone who does not eat meat. But there are several versions and degrees of vegetarian. For example, there are:

Lacto-ovo vegetarians:
A lacto-ovo vegetarian doesn't eat meat, fish or poultry, but eggs, milk and cheese. This is the most common type of vegetarian. A lacto vegetarian or eat milk and cheese products but no eggs while an ovo-vegetarian right again no cheese and milk products but eat eggs.

Pescotariërs and pollotariërs:
A pescotariër do not eat meat, poultry and dairy, but fish while a pollotariër not eat meat, fish and dairy, but poultry, particularly chicken.

Vegans:
Vegans eat no animal products or by-products or use. They eat only vegetables, fruits, nuts, grains and legumes. They also eat no foods where animal products are processed. So, for example, they eat nothing with animal oils is prepared, no mayonnaise because there's egg in and no products with certain E-numbers in it because there for example bone marrow (as in the E number gelatin) in May. Vegans also make no use of utensils in which animal materials. So for example, vegans bear no learning (only cotton shoes and belts, etc.) and also no wool products.

Fruit Aryans and raw food-trailer:
This group of vegetarians is not often. A fruit MEP eat only fruit and nuts. They eat nothing where a plant for should be killed, so only the fruits that can be picked. The reasoning is that this way of eating the most in balance and harmony with the Earth and nature.
A raw food follower eat only raw foods, so only vegetables, fruit, nuts and legumes. According to them disappear the nutritional values from eating when they are purchased.

 

 

22-536 mg vitamine E per dag verlaagt een hartinfarct

Research Question:
Swallowing of vitamin E reduces the chance of getting a heart attack?

Study Design:
This overview article contained 16 Rcts. The dosage ranged between 33 and 800 IU of vitamin e. the follow-up duration ranged between 0.5 and 9.4 years.
1 IU of vitamin E is approximately:

  • 1 mg dl-α tocopherol acetate
  • 0.91 mg dl-α tocopherol
  • 0.67 mg d-α tocopherol (vitamin E in people's mouth)
  • 1.12 mg dl-α tocoferolwaterstofsuccinaat

Results and conclusions:
The researchers found that swallowing vitamin E the chance of getting a heart attack significantly with 18% [RR = 0.82, 95% CI = 0.70-0.96, p = 0.01] reduced.

The researchers found that swallowing vitamin E the chance of getting a fatal heart attacks significantly with 16% [RR = 0.84, 95% CI = 0.73-0.96, p = 0.01] reduced.

The researchers concluded that swallowing 33-800 IE (22.11-536 mg) vitamin a day, reduced the risk of getting a heart attack. However, this reduced risk disappeared when vitamin E was combined with other antioxidants. 

Original title:
Supplementation with vitamin e alone is associated with reduced myocardial infarction: a meta-analysis by Loffredo L, Perri L, [...], Violi f.

Link:
http://www.nmcd-journal.com/article/S0939-4753%2815%2900024-1/abstract

Additional information about El Mondo:
Find here more studies on vitamin E and prevent a heart attack.

Een laag vitamine B12-gehalte verhoogt leeftijdsgebonden maculaire degeneratie

Research Question:
There are conflicting results about the association between plasma homocysteine (tHcy) and the vitamin B content and getting the age-related macular degeneration (AMD). It was therefore carried out this review article.

Raise a high homocysteine and low vitamin B content the chance of getting the age-related macular degeneration?

Study Design:
This overview article contained 11 studies on homocysteine levels with a total of 1072 cases with age-related macular degeneration and 1202 cases without age-related macular degeneration and 3 studies on folic acid and vitamin B12 levels with a total of 152 cases with age-related macular degeneration and 98 cases without age-related macular degeneration.

Results and conclusions:
The researchers found that homocysteine levels of people with age-related macular degeneration signficant 2.67 μmol/L [95% CI = 1.60-3.74, I2 = 92%, p 0.00001] was higher than of people without age-related macular degeneration.

The researchers found that vitamin B12 levels of people with age-related macular degeneration 64.16 pg/mL [95% CI = 19.32-109.00, I2 = 35%, p = 0.19] was lower than of people without age-related macular degeneration.

The researchers found that the folic acid content of people with the wet form of age-related macular degeneration 1.66 ng/mL [95% CI = 0.10-3.99] was lower than of people without age-related macular degeneration.

The researchers concluded that a high homocysteine or low vitamin B12 levels the chance of getting the increased age-related macular degeneration.

Original title:
Homocysteine and the risk of age-related macular degeneration: a systematic review and meta-analysis by Huang P, Wang F, [...], Sun X.

Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508850/

Additional information about El Mondo:
Find here more studies about lowering homocysteine levels and raising the folic acid and vitamin B12 levels.

100 gram vis per week verlaagt leverkanker

Research Question:
Eating fish reduces the chances of getting liver cancer?

Study Design:
This overview article contained 5 retrospective patient-control studies and 5 prospective cohort studies with a total of 3624 liver cancer patients.

Results and conclusions:
The researchers found in case-control studies that eating a lot of fish compared to little, the chances of getting liver cancer are not significantly by 21% [RR = 0.79, 95% CI = 0.59-1.06] reduced.

The researchers found in cohort studies that eating a lot of fish compared to little, the chances of getting liver cancer significantly with 18% [RR = 0.82, 95% CI = 0.70-0.96] reduced.

The researchers found when all studies were combined, that eating a lot of fish compared to little, the chances of getting liver cancer significantly with 18% [RR = 0.82, 95% CI = 0.71-0.94, I2 = 12.8%, p = 0.33] reduced.

The researchers found that the reduced risk remained significant in both stratified as sensitivity analyses.

The researchers found that 1 serving of fish per week the chance of getting leverkaner significantly with 6% [RR = 0.94, 95% CI = 0.91-0.98, I2 = 0.0%, p = 0.74] reduced.

The researchers concluded that eating 1 serving (100 grams) of fish per week reduced the chances of getting liver cancer.

Original title:
Fish intake and risk of liver cancer: a meta-analysis by Huang RX, Duan YY and Hu Yes.

Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304705/

Additional information about El Mondo:
Find here more studies on the occurrence of cancer and fish consumption.

 

Veel foliumzuur, vitamine D, B6 en B2 via voeding verlaagt dikke darmkanker

Research Question:
Eating vitamins lowers the chances of getting colon cancer?

Study Design:
This overview article contained 74 articles (cohort studies).

Results and conclusions:
The researchers found the highest folate intake via diet compared with the lowest intake, a significantly reduced risk of 12% [multivariable-adjusted RR = 0.88, 95% CI = 0.81-0.95] for colon cancer.

The researchers found the highest vitamin D intake through diet compared with the lowest intake, a significantly reduced risk of 13% [multivariable-adjusted RR = 0.87, 95% CI = 0.77-0.99] for colon cancer.

The researchers found the highest vitamin B6 intake via diet compared with the lowest intake, a significantly reduced risk of 12% [multivariable-adjusted RR = 0.88, 95% CI = 0.79-0.99] for colon cancer.

The researchers found the highest vitamin B2 intake via diet compared with the lowest intake, a significantly reduced risk of 14% [multivariable-adjusted RR = 0.86, 95% CI = 0.76-0.97] for colon cancer.

However, the researchers found no link between vitamin A, B12, C, or E-intake via diet and the risk of getting colon cancer.

The researchers concluded that eating a lot of folic acid, vitamin D, B6 and B2 the chance of getting colon cancer reduced.

Original title:
Vitamin and multiple-vitamin supplement intake and incidence of colorectal cancer: a meta-analysis of cohort studies by Liu Y, Yu Q, [...], Li k.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/25491145

Additional information about El Mondo:
Find here more studies on colon cancer and vitamins.
This meal contains a lot of vitamin D and B6.

Dagelijks 300 gram fruit of 400 gram groenten verlaagt coronaire hartziekte

Research Question:
Observational studies suggest an association between fruit and vegetable consumption and coronary heart disease (CHD). However, the results are inconsistent. It was therefore carried out this review article.

Eating fruits and vegetables lowers the chances of getting coronary heart disease?

Study Design:
This overview article contained 23 prospective studies with 937665 participants, of which 18047 patients with coronary artery disease.

Results and conclusions:
The researchers found that eating lots of fruits and vegetables the chance of getting a coronary heart disease significantly with 16% [RR = 0.84, 95% CI = 0.79-0.90] reduced.

The researchers found that eating lots of fruits the chance of getting a coronary heart disease significantly with 14% [RR = 0.86, 95% CI = 0.82-0.91] reduced.

The researchers found that eating lots of vegetables the chance of getting a coronary heart disease significantly with 13% [RR = 0.87, 95% CI = 0.81-0.93] reduced.

The researchers found that eating 477 grams of fruit and vegetables per day the chances of getting coronary artery disease significantly with 12% [RR = 0.88, 95% CI = 0.85-0.91] reduced.

The researchers found that eating 300 grams of fruit per day the chances of getting coronary artery disease significantly with 16% [RR = 0.84, 95% CI = 0.75-0.93] reduced.

The researchers found that eating 400 g of vegetables per day the chances of getting coronary artery disease significantly with 18% [RR = 0.82, 95% CI = 0.73-0.92] reduced.

The researchers found in the subgroup analysis that eating fruits and/or vegetables the chances of getting coronary artery disease among Europeans but not under Asians reduced.

The researchers concluded that eating vegetables and/or fruit the chance of getting a reduced coronary artery disease, especially among Asians.

Original title:
Or fruit and vegetable consumption and risk of coronary heart disease: A meta-analysis of prospective cohort studies by Gan Y, Tong X, [...], Lu Z.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/25662075

Additional information about El Mondo:
Find here more studies on eating fruits and vegetables and heart disease.

Een zinktekort leidt tot hartinfarct

Research Question:
A zinc deficiency increases the chance of getting a heart attack?

Study Design:
This overview article contained 41 case-control studies with 2886 participants.

Results and conclusions:
The researchers found that patients who had a heart attack have low zinc status (less zinc in the body) [SMD =-1,148, 95% CI =-2,365 to-1,331] had than healthy people. 

The researchers found in the subgroup analysis that patients who have had a heart attack a low serum zinc status [SMD =-1,764, 95% CI =-2,417 to-1.112] had than healthy people. 

The researchers found in the subgroup analysis that patients who have had a heart attack her a low zinc status [SMD =-3.326, 95% CI = 4.616-to-2.036] had than healthy people. 

The researchers found that both men in the subgroup analysis [SMD =-3,350, 95% CI =-149 to-1,348] and women [SMD =-1,652, 95% CI =-3,440 to-1922] who have had a heart attack had a low zinc status than healthy people.

The researchers found in the subgroup analysis that the zinc status in Asian patients who have had a heart attack, lower than in European patients.

The researchers concluded that there is a significant relationship existed between zinc deficiency and getting a heart attack.

Original title:
Deficient Zinc Levels and Myocardial Infarction: Association Between Deficient Zinc Levels and Myocardial Infarction: a Meta-analysis by Liu B, Cai ZQ and Zhou YM.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/25627421

Additional information about El Mondo:
Find here more studies on zinc and prevent a heart attack.

Minimaal 100 gram vis per week verlaagt de ziekte van Alzheimer

Research Question:
Lowers eating fish or long chain omega-3 fatty acids the chances of getting Alzheimer's disease?

Study Design:
This overview article contained prospective cohort studies.
There was a low heterogeneity between the studies and within the subgroups.                                                                                              

Results and conclusions:
The researchers found that both eating lots of long chain omega-3 fatty acids as fish the chance of getting dementia not significantly reduced [RR respectively = 0.97, 95% CI = 0.85-1.10 and RR = 0.84, 95% CI = 0.71-1.01].

The researchers found that eating a lot of long chain omega-3 fatty acids, the chances of getting Alzheimer's disease are not significantly by 11% [RR = 0.89, 95% CI = 0.74-1.08] reduced.
Not significant is, there cannot be said with 95% reliability that eating lots of long chain omega-3 fatty acids, the chances of getting Alzheimer's disease reduced.

The researchers found that eating a lot of fish, the chances of getting Alzheimer's disease significantly with 36% [RR = 0.64, 95% CI = 0.44-0.92] reduced.

The researchers found that eating 100 grams of fish per week, the chances of getting Alzheimer's disease significantly with 11% [RR = 0.89, 95% CI = 0.79-0.99] reduced.

The researchers concluded that eating a lot of fish (at least 100 grams per week) the chances of getting Alzheimer's disease (and not dementia) reduced.

Original title:
Omega-3 fatty acids intake and risks of dementia and Alzheimer's disease: A meta-analysis by Wu S, Thing Y, [...], Mao P.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/25446949

Additional information about El Mondo:
Find here more studies eating fish.