Chronic diseases

Objectives:

Objectives:
Is hypertension a risk factor in adults with cerebral palsy?

Study design:
This review article included data from 11 international cohort studies representing 444 adults with cerebral palsy [median (IQR) age of the sample was 29.0 (23.0-38.0), 51% men, 89% spastic type, Gross Motor Function Classification System levels I-V].

Objectives:
The efficacy of soy diet for nonalcoholic fatty liver disease remains controversial. Therefore, this review article has been conducted.

Does soy supplementation have positive effects on nonalcoholic fatty liver disease?

Study design:
This review article included 5 RCTs.
All of 5 RCTs have a relatively small sample size (n 100).

Jadad scores of the 5 included studies vary from 3 to 5 and all 5 studies were considered to be high-quality ones according to quality assessment.

Objectives:
Do critically ill patients benefit of thiamine (vitamin B1) supplementation?

Study design:
This review article included 8 RCTs and 10 cohort studies.

Results and conclusions:
The investigators found in the analysis of RCTs, that thiamine supplementation showed a significantly 42% lower odds of developing ICU delirium [OR = 0.58, 95% CI = 0.34 to 0.98].

Objectives:
Do patients with knee osteoarthritis benefit from vitamin D supplementation?

Study design:
This review article included 6 articles with a total of 1,599 patients with osteoarthritis of the knee.

Objectives:
Zinc in one of the most abundant trace minerals in human body which is involved in numerous biological pathways and has variety of roles in the nervous system. It has been assumed that zinc exerts its role in nervous system through increasing brain derived neurotrophic factor (BDNF) concentrations. Therefore, this review article has been conducted.

Objectives:
Whether N-acetylcysteine (NAC) therapy can promote the improvement of clinical symptoms and lung function in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has not been verified by large-scale randomized controlled trials, only a few small sample studies. Therefore, this review article has been conducted.

Objectives:
Selenium (Se) is a trace element having significant effects on human metabolism. Recent studies suggest that selenium supplementation have a pivotal effect on the inflammatory markers. Therefore, this review article has been conducted.

Objectives:
Vitamin D deficiency is frequently associated with several medical conditions. However, a comprehensive meta-analysis assessing the association between vitamin D level and acne is lacking. Therefore, this review article (meta-analysis) has been conducted.

Does a low vitamin D level (expressed as circulating 25(OH)D levels) increase risk of both acne and acne severity?

Study design:
This review article included 13 articles with a total of 1,362 acne patients and 1,081 healthy controls (persons without acne).

Objectives:
The association between serum 25-hydroxyvitamin D 25(OH)D level (vitamin D level in blood) and asthma occurrence in children was controversial. Therefore, this review article has been conducted.