Voeding en gezondheid

200-1000 mg vitamine C per dag verlaagt de oxidatieve stress

Research Question:
How many mg of vitamin C per day is needed to reduce the increased oxidative stress among athletes?

Study Design:
This overview article contained 12 studies. They were crossover or Rcts. The vitamin C supplementation period ranged from acute to 5 months.

 

Results and conclusions:
Antioxidants supplements are widely used by athletes in order to avoid the increased oxidative stress. The increased oxidative stress leads to muscle damage, a lowered immune system and fatigue.

The researchers conclude that 200-1000 mg of vitamin C per day reduces the oxidative stress while more than 1000 mg per day seems to reduce the training-induced adaptations by decreasing the mitochondrial biogenesis or by any changes of the vascular function.

200 mg of vitamin C per day, obtained by five servings of fruits and vegetables, may be enough to reduce the oxidative stress without the threshold adjustments to exceed the optimal training harms.

During periods of increased oxidative stress athletes can benefit from swallowing more than 200 mg of vitamin C per day for 1 to 2 weeks.

Original title:
Effect of Vitamin C Supplements on Physical Performance by Ballard AJ.

Link:

http://journals.lww.com/acsm-csmr/Fulltext/2012/07000/Effect_of_Vitamin_C_Supplements_on_Physical.8.aspx

Additional information about El Mondo:
Oxidative stress is caused by an imbalance between pro-oxidants and antioxidants. This imbalance can be caused by an increased level of reactive oxygen particles and/or reactive nitrogen particles or a decrease in antioxidant in the immune system. Antioxidants include vitamin C, E, zinc, beta carotene and flavonoids. Pro-oxidants include exhaust fumes, cigarette smoke, particulate matter.

 

Foliumzuursupplementen verlagen het homocysteïnegehalte bij mensen met suikerziekte type 2

Research questi
on: the evidence for the effects of folic acid on plasma homocysteine levels and the total the glycemic control in people with type 2 diabetes are contradictory. It was therefore carried out this review ar

ticle.The total plasma homocysteine levels and folic acid supplements improve the glycemic control in people with type 2 diabetes

?Study desig
n: this overview article contained 4 studies with 183 patients with diabetes ty

pe 2. results and conclu
sions: the meta-analysis showed that folic acid supplements had a significant effect on the total plasma homocysteine levels in patients with type 2 diabetes. The weighted mean difference was-3.52 [95% CI =-4.44 to-2.60]. Significant is, there is a link at 95% reliability.

The meta-analysis showed that folic acid supplements had a non-significant effect on the HbA1c levels in patients with type 2 diabetes. The weighted mean difference was-0.37 [95% CI =-1.10 to 0.35]. Non-significant is, there is no link.

The researchers concluded that folic acid supplements the total plasma homocysteine levels in patients with type 2 diabetes reduced and there was a trend to recognize in improving glycemic control.Original title: Eff

ect of folic acid sup
plementation on plasma total homocysteine levels and glycemic control in patients with type 2 diabetes: A systematic review and meta-analysis by Sudchada P, Saokaewemail S, [...], http://www.sciencedirect.co

m/sci
ence/article/pii/S016882271200215XExtra information from Khaith

ong w. Link: El Mondo: read m
ore about folic acid and homocysteine levels in the presentation the high folic acid.