5 most common long-term effects of COVID-19 are fatigue, headache, attention disorder, hair loss and dyspnea

Afbeelding

Objectives:
What are the long-term effects of COVID-19 and the prevalence of each symptom, sign or laboratory parameter of patients at a post-COVID-19 stage?

Study design:
This review article included 15 studies.
The prevalence of 55 long-term effects was estimated, 21 meta-analyses were performed, and 47,910 patients were included.
The follow-up time ranged from 15 to 110 days post-viral infection.
The age of the study participants ranged between 17 and 87 years.
All meta-analyses showed medium (n=2) to high heterogeneity (n=13).
Regarding the quality of the studies, all had a score of 8 or more.

Results and conclusions:   
The investigators found that 80% [95% CI = 65 to 92] of the patients that were infected with SARS-CoV-2 (COVID-19) developed one or more long-term symptoms.
The 5 most common symptoms were fatigue (58%), headache (44%), attention disorder (27%), hair loss (25%) and dyspnea (24%).

The investigators concluded the 5 most common long-term effects of COVID-19 are fatigue, headache, attention disorder, hair loss and dyspnea. More evidence and research from multi-disciplinary teams are crucial to understanding the causes, mechanisms and risks to develop preventive measures, rehabilitation techniques and clinical management strategies with whole-patient perspectives designed to address the after-COVID-19 care. From the clinical point of view, physicians should be aware of the symptoms, signs and biomarkers present in patients previously affected by COVID-19 to promptly assess, identify and halt long COVID-19 progression, minimize the risk of chronic effects and help reestablish pre-COVID-19 health.  

Original title:
More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis by Lopez-Leon S, Wegman-Ostrosky T, [..], Villapol S.

Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852236/

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