Nutritional Advice El Mondo
Objectives:
Coronavirus disease 2019 (COVID-19) is an emerging disease that was first reported in Wuhan city, the capital of Hubei province in China and has subsequently spread worldwide. Risk factors for mortality have not been well summarized. Therefore, this review article has been conducted.
What are the risk factors for mortality from COVID-19 infection?
Study design:
This review article included 14 studies with 29,909 COVID-19 infected patients and 1,445 cases of death.
There was no evidence of publication bias.
Results and conclusions:
The investigators found a significant association between older age (≥65 vs 65 years old) [pooled ORs = 4.59, 95% CI = 2.61 to 8.04, p 0.001], gender (male vs female) [pooled ORs = 1.50, 95% CI = 1.06 to 2.12, p = 0.021] and risk of death from COVID-19 infection.
The investigators found, in addition, hypertension [pooled OR = 2.70, 95% CI = 1.40 to 5.24, p = 0.003], cardiovascular diseases (CVDs) [pooled OR = 3.72, 95% CI = 1.77 to 7.83, p = 0.001], diabetes [pooled OR = 2.41, 95% CI = 1.05 to 5.51, p = 0.037], chronic obstructive pulmonary disease (COPD) [pooled ORs = 3.53, 95% CI = 1.79 to 6.96, p 0.001] and cancer [pooled OR = 3.04, 95% CI = 1.80 to 5.14, p 0.001], were associated with a higher risk of mortality from COVID-19 infection.
The investigators found findings from sensitivity analysis showed that overall estimates on the association of demographic characteristics and comorbidities with COVID-19 mortality did not depend on a single study.
The investigators concluded older age (≥65 years old), male gender, hypertension, cardiovascular diseases, diabetes, COPD and malignancies are associated with a greater risk of death (mortality) from COVID-19 infection. These findings could help clinicians to identify patients with poor prognosis at an early stage.
Original title:
Risk Factors for Mortality in Patients With Coronavirus Disease 2019 (COVID-19) Infection: A Systematic Review and Meta-Analysis of Observational Studies by Parohan M, Yaghoubi S, […], Djalali M.
Link:
https://www.tandfonline.com/doi/full/10.1080/13685538.2020.1774748
Additional information of El Mondo:
Find more information/studies on coronavirus right here.