Nutritional Advice El MondoObjectives:
The association between acute kidney injury (AKI) and outcome of coronavirus disease 2019 (COVID-19) has not yet been conclusively established. Therefore, this review article has been conducted.
Is acute kidney injury associated with worse prognosis in COVID-19 patients?
Study design:
This review article included 15 studies (cohort or case-control studies) with a total of 5,832 COVID-19 patients.
Results and conclusions:
The investigators found overall, acute kidney injury was associated with over 18-fold enhanced risk of COVID-19 severity [OR = 18.5, 95% CI = 8.99 to 38.08, I2 = 0%].
The investigators found overall, acute kidney injury was associated with over 23-fold enhanced risk of COVID-19 mortality [OR = 23.9, 95% CI = 18.84 to 30.31, I2 = 0%].
The investigators concluded acute kidney injury (AKI) is associated with worse prognosis in COVID-19 patients. Further investigation of the underlying mechanism of renal disease in COVID-19 would be needed to clarify possible therapeutic targets. Acute kidney injury could be used as a clinical characteristic in severity classification and risk stratification.
Original title:
Acute Kidney Injury is Associated with Worse Prognosis In COVID-19 Patients: A Systematic Review and Meta-analysis by Cheruiyot I, Henry B, […], Misiani M.
Link:
https://pubmed.ncbi.nlm.nih.gov/32921724/
Additional information of El Mondo:
Find more information/studies on coronavirus right here.