Cancer

Cancer

The human body consists of organs like liver, lungs and heart. Organs consists of tissues, and tissue consists of cells. Under normal circumstances cells only divide when needed, e.g. at recovery, growth and wound healing. This process is also called controlled cell division. Controlled cell division is necessary and innocent. However, it becomes dangerous when cell division within a particular organ is no longer under control. In that case, is called cancer. Cancer is a disorder, characterized by uncontrolled cell division in a particular organ.

Cancer

Scientific studies (review articles) on the relationship between diet/nutrients and cancer prevention:
One swallow does not make a summer. A famous Dutch saying that could not be any more obvious. Just because one single scientific study about a certain topic makes certain claims, it does not necessarily mean it is true. On the other hand, a review article (a collection of scientific studies on a certain topic) of randomized, placebo-controlled double blind clinical trials (RCTs) will answer the following question:

Elevated serum selenium levels may decrease high-grade prostate cancer among current and former smokers

Objectives:
Some observational studies have shown that elevated serum selenium levels are associated with reduced prostate cancer risk. However, not all published studies support these results. Therefore, this review article (meta-analysis) has been conducted.

Does an elevated serum selenium level reduce prostate cancer risk?

Study design:
This review article included 12 case-control studies, 4 cohort studies and 1 RCT with 6,136 prostate cancer cases among 34,901 participants.

20 mg/d isoflavones dieatary intake reduces risk of colorectal neoplasms in Asians

Objectives:
Epidemiological studies suggest that soya consumption as a source of phyto-oestrogens and isoflavones may be associated with a reduced risk of colorectal cancer. However, findings have not yet been synthesised for all groups of phyto-oestrogens. Therefore, this review article (meta-analysis) has been conducted.

Does soya consumption reduce colorectal cancer risk?

Study design:
This review article included 16 studies (case-control studies and cohort studies).

Daily 2 mg dietary vitamin E intake reduces lung cancer risk

Objectives:
Several epidemiological studies investigating the association between dietary vitamin E intake and the risk of lung cancer have demonstrated inconsistent results. Therefore, this review article (meta-analysis) has been conducted.

Does dietary vitamin E intake reduce lung cancer risk?

Study design:
This review article included 9 cohort studies with 4,164 lung cancer cases among 435,532 participants.

The Egger’s test showed no evidence of publication bias [t = 1.24, p = 0.246].

A high total fat consumption increases non-Hodgkin's lymphoma

Objectives:
Many studies suggest that high-fat diets are linked to the etiology of non-Hodgkin's lymphoma (NHL). However, the findings are inconsistent and therefore the association between fat and non-Hodgkin's lymphoma remains unclear. Therefore, this review article (meta-analysis) has been conducted.

Does a high fat dietary intake increase non-Hodgkin's lymphoma risk?

Study design:
This review article included two cohort studies and eight case-control studies.

The funnel plot revealed no evidence for publication bias.