Cancer has a significant impact on mortality rate in COVID-19 patients

Objectives:
What is the impact of cancer on serious events including ICU admission rate and mortality in COVID 19 patients?

Study design:
This review article included 13 studies with a total of 3,775 COVID-19 patients, of whom 63 (1.66%) had a cancer.

Results and conclusions:   
The investigators found pooled estimates of ICU admission in COVID 19 patients with and without cancer were 40% versus 8.42%.

The investigators found odds ratio of ICU admission rates between the cancer and non-cancer groups was 2.88 [95% CI =1.18 to 7.01, p = 0.026].

The investigators found pooled estimates of death rate in COVID -19 patients with and without cancer were 20.83% versus 7.82%.

The investigators found odds ratio of death rates between the cancer and non-cancer groups was 2.25 [95% CI = 0.71 to 7.10, p = 0.166].

The investigators found pooled prevalence of cancer patients was 2% [95 CI = 1 to 4].

The investigators concluded presence of cancer in COVID-19 leads to higher risk of developing serious events i.e. ICU admission, mechanical ventilation and mortality. The presence of cancer has a significant impact on mortality rate in COVID-19 patients.

Original title:
Impact of COVID -19 in cancer patients on severity of disease and fatal outcomes: A systematic review and meta-analysis by Salunke AA, Nandy K, […], Pandya S.

Link:
https://pubmed.ncbi.nlm.nih.gov/32755847/

Additional information of El Mondo:
Find more information/studies on cancer and coronavirus right here.