Children account for a small proportion of COVID-19 in household transmission cluster

Afbeelding

Objectives:
The role of children in the spread of SARS-CoV-2 (COVID-19) remains highly controversial. Therefore, this review article has been conducted.

What is the role of children in SARS-CoV-2 in household transmission cluster?

Study design:
This review article included household SARS-CoV-2 transmission clusters (n = 213 from 12 countries).

Results and conclusions:   
The investigators found only 8 (3.8%) transmission clusters were identified as having a paediatric index case.

The investigators found asymptomatic index cases were associated with a lower secondary attack in contacts than symptomatic index cases [estimate risk ratio = 0.17, 95% CI = 0.09 to 0.29].

The investigators found the secondary attack rate in paediatric household contacts was lower than in adult household contacts [estimate risk ratio = 0.62, 95% CI = 0.42 to 0.91].

The investigators concluded that children account for a small proportion of SARS-CoV-2 (COVID-19) in household transmission cluster. These findings have important implications for the ongoing management of the COVID-19 pandemic, including potential vaccine prioritization strategies.

Original title:
A meta-analysis on the role of children in SARS-CoV-2 in household transmission cluster by Zhu Y, Bloxham CJ, […], Short KR.

Link:
https://pubmed.ncbi.nlm.nih.gov/33283240/

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