Nutritional Advice El Mondo
Objectives:
Results from earlier publications on the association of coffee and caffeine and risk of ovarian cancer are inconsistent. Therefore, this review article has been conducted.
Is there an association between coffee and caffeine consumption and risk of ovarian cancer among women?
Study design:
This review article included 22 case-control studies with a total of 40,140 participants, of which 8,568 patients with ovarian cancer. The participants were ≥ 17 years.
Results and conclusions:
The investigators found combining 21 effect sizes from 18 studies, no significant association was observed between total coffee consumption and risk of ovarian cancer [OR = 1.09, 95% CI = 0.94 to 1.26].
The investigators found no significant association between total caffeine intake and ovarian cancer risk [OR = 0.89, 95% CI = 0.55 to 1.45].
The investigators found, in addition, caffeinated coffee intake was not significantly associated with ovarian cancer risk [OR = 1.05, 95% CI = 0.87 to 1.28].
The investigators found, however, combining effect sizes from 5 studies, an inverse significant association between decaffeinated coffee intake and risk of ovarian cancer [OR = 0.72, 95% CI = 0.58 to 0.90].
The investigators concluded decaffeinated coffee consumption could reduce risk of ovarian cancer among women. Could reduce because this review article only included case-control studies and no cohort studies.
Original title:
Coffee and caffeine intake and risk of ovarian cancer: a systematic review and meta-analysis by Shafiei F, Salari-Moghaddam A , […], Esmaillzadeh A.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/30833443
Additional information of El Mondo:
Find more information/studies on coffee consumption, review article/significantly and cancer right here.