Nutritional Advice El Mondo
Objectives:
The number of positive and death cases from coronavirus disease 2019 (COVID-19) is still increasing until now. One of the most prone individuals, even in normal situations is patients with dementia. Currently, no study provides clear evidence regarding the link between dementia and COVID-19. Therefore, this review article has been conducted.
Is dementia associated with poor outcomes of COVID-19 infection?
Study design:
This review article included 24 studies with a total of 4648,247 sample size and 46,391 dementia patients. Of a total of 24 included studies, 21 were retrospective cohort, 2 studies were prospective cohort, while the remaining 1 study was a case-control study.
All included studies were rated “good”.
There was no indication of publication bias.
Results and conclusions:
The investigators found that dementia was associated with composite poor outcome [RR = 2.67, 95% CI = 2.06 to 3.47, p 0.00001, I2 = 99%, random-effect modeling] and its subgroup which comprised of risk of COVID-19 infection [RR = 2.76, 95% CI = 1.43 to 5.33, p = 0.003, I2 = 99%, random-effect modeling], severe COVID-19 [RR = 2.63, 95% CI = 1.41 to 4.90, p = 0.002, I2 = 89%, random-effect modeling] and mortality from COVID-19 infection [RR = 2.62, 95% CI = 2.04 to 3.36, p 0.00001, I2 = 96%, random-effect modeling].
The investigators concluded that dementia is associated with an enhanced risk of severity and mortality from COVID-19 infection. Therefore, extra care and close monitoring should be provided to patients with dementia to minimize the risk of infections, preventing the development of severe and mortality outcomes.
Original title:
Dementia and outcomes from coronavirus disease 2019 (COVID-19) pneumonia: A systematic review and meta-analysis by Hariyanto TI, Putri C, […], Kurniawan A.
Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674980/
Additional information of El Mondo:
Find more information/studies on coronavirus right here.