Face mask with or without hand wash does not reduce influenza-like illness in community settings

Afbeelding

Objectives:
Does face mask with or without hand wash reduce influenza-like illness (ILI) in community settings?

Study design:
This review article included 9 cluster RCTs. Of the 9 RCTs, 6 were done in household setting and 2 were done with university students as participants in university residence halls.
6 of these studies compared three arms of intervention - hand hygiene (hand wash) alone, both hand hygiene and triple-layered facial mask versus no intervention.
Risk of bias was assessed as low (n = 4), medium (n = 3) or high (n = 1) risk.

Publication bias was not significant.

Results and conclusions:   
The investigators found no significant association between face mask use and decrease in events of influenza-like illness (ILI) [pooled effect size = -0.17, 95% CI = -0.43 to 0.10, p = 0.23, I2 = 10.9%, n = 5].

The investigators found no significant association between face mask with hand wash and decrease in events of influenza-like illness (ILI) [pooled effect size = -0.09, 95% CI = -0.58 to 0.40, p = 0.71, I2 = 69.4%, n = 6].

The investigators concluded randomized control trials (RCTs) do not show any significant reduction of influenza-like illness (ILI) by the use of face mask with or without hand hygiene (hand wash) in community settings. Well-conducted clinical studies are warranted to determine whether these results can be applied to the COVID-19 pandemic.

Original title:
Facemasks for prevention of viral respiratory infections in community settings: A systematic review and meta-analysis by Aggarwal N, Dwarakanathan V, [...], Ray A.

Link:
https://pubmed.ncbi.nlm.nih.gov/32496254/?from_single_result=Facemasks+for+prevention+of+viral+respiratory+infections+in+community+settings%3A+A+systematic+review+and+meta-analysis

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