Nutritional Advice El Mondo
Objectives:
Famotidine was reported to potentially provide benefits to Coronavirus Disease 2019 (COVID-19) patients. However, it remains controversial whether it is effective in treating COVID-19. Therefore, this review article has been conducted.
Does famotidine reduce the risk of developing serious illness, death and intubation for COVID-19 patients?
Study design:
This review article included 5 studies with a total of 36,635 COVID-19 patients.
Results and conclusions:
The investigators found that famotidine use was associated with a statistically non-significant reduced risk of progression to severe disease, death and intubation for COVID-19 patients [pooled RR = 0.82, 95% CI = 0.52 to 1.30, p = 0.40].
Non-significant means that there is no association with a 95% confidence.
The investigators concluded famotidine has no significant protective effect in reducing the risk of developing serious illness, death and intubation for COVID-19 patients. More original studies are needed to further clarify whether it is associated with reduced risk of the severity, death and intubation for COVID-19 patients.
Original title:
Does Famotidine Reduce the Risk of Progression to Severe Disease, Death, and Intubation for COVID-19 Patients? A Systemic Review and Meta-Analysis by Sun C, Chen Y, […], Zhou Q.
Link:
https://pubmed.ncbi.nlm.nih.gov/33625613/
Additional information of El Mondo:
Find more information/studies on corona virus right here.
Intubation is the process of inserting a tube, called an endotracheal tube (ET), through the mouth and then into the airway.
Famotidine is a histamine-2 blocker that works by decreasing the amount of acid the stomach produces. Famotidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome.
Famotidine belongs to a class of drugs known as H2 blockers.