Nutritional Advice El Mondo
Objectives:
Several studies have been published about the effect of garlic on lipid profile and blood glucose in diabetic patients. Which, the results mostly contradict with each other. Therefore, this review article has been conducted.
Does garlic improve lipid profile and blood glucose in diabetic patients?
Study design:
This review article included 33 articles with a total of 1,273 individuals, with a mean of 39 samples per study.
Results and conclusions:
The investigators found the concentration of serum total cholesterol significantly decreased wih 16.87 mg/dL [95% CI = -21.01 to -12.73, p = 0.001] in the garlic group when compared with the placebo group.
The investigators found the concentration of serum LDL cholesterol (bad cholesterol) significantly decreased with 9.65 mg/dL [95% CI = -15.07 to -4.23, p = 0.001] in the garlic group when compared with the placebo group.
The investigators found the concentration of serum triglycerides significantly decreased with 12.44 mg/dL [95% CI = -18.19 to -6.69, p = 0.001] in the garlic group when compared with the placebo group.
The investigators found the concentration of serum HDL cholesterol (good cholesterol) significantly increased with 3.19 mg/dL [95% CI = 1.85 to 4.53, p = 0.001] in the garlic group when compared with the placebo group.
The investigators found the concentration of serum fasting blood sugar significantly decreased with 10.90 mg/dL [95% CI = -16.40 to -5.40, p = 0.001] in the garlic group when compared with the placebo group.
The investigators found the concentration of serum HbA1c significantly decreased with 0.60 mg/dL [95% CI = -0.98 to -0.22, p = 0.001] in the garlic group when compared with the placebo group.
The investigators concluded that garlic improves lipid profile as well as glucose parameters and can be therapeutically effective in patients suffering from cardiovascular diseases and diabetes.
Original title:
The effect of garlic on lipid profile and glucose parameters in diabetic patients: A systematic review and meta-analysis by Shabani E, Sayemiri K and Mohammadpour M.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/30049636
Additional information of El Mondo:
Find more information/studies on diabetes, cholesterol, meta-analyses/heterogeneity and garlic right here.