Nutritional Advice El Mondo
Objectives:
Does hepatitis C virus (HCV) infection increase risk of pancreatic cancer (PAC)?
Study design:
This review article included 8 cohort and 8 case-control studies.
Results and conclusions:
The investigators found hepatitis C virus infection significantly increased risk of pancreatic cancer with 51% [pooled OR = 1.51, 95 % CI = 1.31 to 1.74, I2 = 63.49%, p 0.001].
However, studies that adjusted their results for diabetes, chronic pancreatitis, alcohol intake and smoking showed lower ORs than studies that did not adjust for them.
The investigators concluded hepatitis C virus infection is associated with increased risk of pancreatic cancer, but this association is attenuated among studies that adjusted their results for potential risk factors for pancreatic cancer. Therefore, future prospective cohort studies are needed to confirm this association.
Original title:
Hepatitis C virus infection and risk of pancreatic cancer: A meta-analysis by Arafa A, Eshak ES, […], Anwar MM.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/32088651
Additional information of El Mondo:
Find more information/studies on malnutrition, vaccination and cancer right here.