Nutritional Advice El MondoObjectives:
Coronavirus disease 2019 (COVID-19) has been reported to cause worse outcomes in patients with underlying cardiovascular disease, especially in patients with acute cardiac injury, which is determined by elevated levels of high-sensitivity troponin. There is a paucity of data on the impact of congestive heart failure (CHF) on outcomes in COVID-19 patients. Therefore, this review article has been conducted.
What is the impact of congestive heart failure (CHF) on outcomes in COVID-19 patients?
Study design:
This review article included 20 individual studies with a total of 5,967 COVID-19 patients.
Results and conclusions:
The investigators found that both non-survivors and those with severe disease had an increased risk of acute cardiac injury and cardiac arrhythmias [relative risk (RR) = -8.52, 95% CI = 3.63 to 19.98, p 0.001 and 3.61, 95% CI = 2.03 to 6.43, p = 0.001], respectively.
The investigators found mean difference in the levels of Troponin-I, CK-MB and NT-proBNP was higher in deceased and severely infected patients.
The investigators found the RR of in-hospital mortality was 2.35 [95% CI = 1.18 to 4.70, p = 0.022) and 1.52 [95% CI = 1.12-2.05, p = 0.008] among patients who had pre-existing congestive heart failure and hypertension, respectively.
The investigators concluded that cardiac involvement in COVID-19 infection appears to significantly adversely impact patient prognosis and survival. Pre-existence of congestive heart failure and high cardiac biomarkers like NT-pro BNP and CK-MB levels in COVID-19 patients correlates with worse outcomes.
Original title:
Impact of congestive heart failure and role of cardiac biomarkers in COVID-19 patients: A systematic review and meta-analysis by Dalia T, Lahan S, […], Shah Z.
Link:
https://pubmed.ncbi.nlm.nih.gov/33714416/
Additional information of El Mondo:
Find more information/studies on congestive heart failure and coronavirus right here.
B-type natriuretic peptide (BNP) and N-terminal pro b-type natriuretic peptide (NTproBNP) are peptides (small proteins) that are either hormones or part of the peptide that contained the hormone at one time. They are continually produced in small quantities in the heart. High levels can mean your heart isn't pumping as much blood as your body needs. When this happens, it's known as heart failure, sometimes called congestive heart failure.