Nutritional Advice El Mondo
Objectives:
Do higher gestational vitamin D levels (vitamin D levels of the mother during pregnancy) decrease risk of multiple sclerosis (MS) in offspring?
Study design:
This review article included 4 case-control studies of moderate to low risk of bias.
Factors identified as determinants of heterogeneity were the definitions of vitamin D deficiency, the characteristics of study participants and the quality of the study.
Results and conclusions:
The investigators found that higher levels of gestational vitamin D significantly reduced risk of multiple sclerosis in offspring with 37% [OR = 0.63, 95% CI = 0.47 to 0.84] in random effects models and in a stratified analysis based on study quality.
The investigators concluded higher levels of gestational vitamin D reduce risk of multiple sclerosis in offspring.
Original title:
Gestational vitamin D and offspring risk of multiple sclerosis: a systematic review and meta-analysis by Jasper EA, Nidey NL, […], Ryckman KK.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/32014337
Additional information of El Mondo:
Find more information/studies on vitamin D and pregnancy right here.