Nutritional Advice El Mondo
Objectives:
Do HPV vaccines reduce risk of HPV-related oropharyngeal cancer?
Study design:
This review article included 2 randomized controlled trials (RCTs) and 4 cross-sectional studies with a total of 15,240 participants.
Results and conclusions:
The investigators found in a meta-analysis that vaccinated individuals were 46% [risk ratio = 0.54, 95% CI = 0.32 to 0.91, p = 0.02] less likely to develop oral vaccine-type HPV infection compared to controls.
The investigators found in a second meta-analysis of 4 studies (1 randomized controlled trial and 3 cross-sectional studies and 13,285 participants) an 80% [risk ratio = 0.20, 95% CI = 0.09 to 0.43, p 0.0001] less likelihood of oral HPV16 infection.
The investigators concluded that HPV vaccines show protection against oral vaccine-type HPV infection including high-risk HPV16 infection, thus reducing the incidence of HPV-related oropharyngeal cancer (OPC). Vaccination against HPV, especially in males, who are predominantly affected by HPV-related OPC, could result in the prevention of this disease.
Original title:
Human Papillomavirus Vaccine to End Oropharyngeal Cancer. A Systematic Review and Meta-Analysis by Tsentemeidou A, Fyrmpas G, […],Tsetsos N.
Link:
https://pubmed.ncbi.nlm.nih.gov/34110733/
Additional information of El Mondo:
Find more information/studies on RCTs/cohort/significantly/review article, vaccination and malnutrition right here.