Hypertension, diabetes, cardiovascular diseases and chronic kidney disease are risk factors for COVID-19 infection

Afbeelding

Objectives:
What are the clinical characteristics of the patients diagnosed with COVID-19?

Study design:
This review article included 102 studies, covering 121,437 infected COVID-19 patients.

Begg’s funnel plot [p = 0.780] and Egger’s test [p = 0.069], showed no sign of publication bias in the included studies.

Results and conclusions:   
The investigators found the mean age of the patients was 58.42 years.

The investigators found the results indicate a prevalence of 79.26% for fever [95% CI = 74.98 to 83.26, I2 = 97.35%], 60.70% for cough [95% CI = 56.91 to 64.4, I2 = 94.98%], 33.21% for fatigue or myalgia [95% CI = 28.86 to 37.70, I2 = 96.12%], 31.30% for dyspnea [95% CI = 26.14 to 36.69, I2 = 97.67%] and 10.65% for diarrhea [95% CI = 8.26 to 13.27, I2 = 94.20%].

The investigators found the prevalence for the most common comorbidities was 28.30% for hypertension [95% CI = 23.66 to 33.18, I2 = 99.58%], 14.29% for diabetes [95% CI = 11.88 to 16.87, I2 = 99.10%], 12.30% for cardiovascular diseases [95% CI = 9.59 to 15.27, I2 = 99.33%] and 5.19% for chronic kidney disease [95% CI = 3.95 to 6.58, I2 = 96.42%].

The investigators concluded hypertension, diabetes, cardiovascular diseases and chronic kidney disease are risk factors for patients with COVID-19 infection. Furthermore, the results show that an elderly male with underlying diseases is more likely to have severe COVID-19.

Original title:
The prognostic value of comorbidity for the severity of COVID-19: A systematic review and meta-analysis study by Fathi M, Vakili K, […], Eilami O.

Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0246190

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