Nutritional Advice El Mondo
Objectives:
Does influenza vaccination during pregnancy improve child health outcomes?
Study design:
This review article included 15 observational studies and 4 primary RCTs.
Results and conclusions:
The investigators found in a random effects meta-analysis of 2 RCTs including 5,742 participants, maternal influenza vaccination (influenza vaccination during pregnancy) was associated with an overall reduction of infant laboratory confirmed influenza of 34% [95% CI = 15-50%].
However, there was no effect of maternal influenza vaccination on infant laboratory confirmed influenza in infants ≤6 months old.
The investigators found overall observational studies showed an inverse (protective) association between maternal influenza vaccination and infant laboratory confirmed influenza, hospitalisation and clinic visits due to infant laboratory confirmed influenza or influenza-like illness in infants and other respiratory illness in infants ≤6 months old.
The investigators concluded that maternal influenza vaccination is a strategy to reduce infant laboratory confirmed influenza and influenza-related hospitalisations in young infants. Communicating these benefits to pregnant women may support their decision to accept influenza vaccination in pregnancy and increase vaccine coverage in pregnant women.
Original title:
The effectiveness of influenza vaccination in pregnancy in relation to child health outcomes: Systematic review and meta-analysis by Jarvis JR, Dorey RB, […], Jones CE.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/31932138
Additional information of El Mondo:
Find more information/studies on vaccination and pregnancy right here.