Nutritional Advice El Mondo
Objectives:
Patients with pre-existing cardiovascular disease (CVD) might be more susceptible to infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and have higher mortality rates. Nevertheless, the risk of mortality has not been previously quantified. Therefore, this review article has been conducted.
Which are the risk factors of mortality in coronavirus disease 2019 (COVID-19) patients?
Study design:
This review article included 26 studies, encompassing 8,497 COVID-19 patients, of whom 5121 (60.3%) were male and 3376 (39.7%) were female. N
Results and conclusions:
The investigators found males had a significantly 16% higher risk of mortality than females [RR = 1.16, 95% CI = 1.05 to 1.27, p = 0.003] and elderly patients had higher chance of dying than younger patients [MD = -15.72, 95% CI = -18.62 to 12.81, p 0.0001]. Significantly because the calculated p-value of 0.0001 was less than the p-value of 0.05.
The investigators found patients with overall cardiovascular disease (CVD) had a 1.96-fold higher mortality risk [95% CI = 1.51 to 2.54, p 0.0001].
The investigators found coronary artery disease (CAD) significantly increased risk of mortality by 1.90-fold [95% CI = 1.32 to 2.74, p = 0.0005].
The investigators found CVD-CAD significantly increased risk of mortality up to 2.03-fold [95% CI = 1.41 to 2.92, p = 0.0002].
The investigators found hypertension, cerebrovascular disease and diabetes increased the risk of death up to 1.73-fold, 1.76-fold and 1.59-fold, respectively [p 0.0001, p 0.0001, p 0.05, respectively].
The investigators concluded sex, age, presence of coronary artery disease (CAD) and/or other types of cardiovascular disease (CVD), hypertension, cerebrovascular diseases and diabetes mellitus increase mortality in patients with COVID-19. In particular, CAD and/or other types of CVD, hypertension, cerebrovascular diseases almost double the risk of mortality. Further research to identify the underlining mechanisms of such an association is warranted.
Original title:
Quantification of Death Risk in Relation to Sex, Pre-Existing Cardiovascular Diseases and Risk Factors in COVID-19 Patients: Let's Take Stock and See Where We Are by Moula AL, Micali LR, […], Gelsomino S.
Link:
https://www.mdpi.com/2077-0383/9/9/2685/htm
Additional information of El Mondo:
Find more information/studies on diabetes mellitus, cardiovascular disease and coronavirus right here.