Nutritional Advice El Mondo
Objectives:
Females generally have higher antibody responses to viral vaccines. Therefore, this review article has been conducted.
Are there gender differences in the efficacy of the COVID-19 vaccines?
Study design:
This review article included 4 eligible trials with 643,127 participants. All studies were categorized as having a low risk of bias.
Results and conclusions:
The investigators found COVID-19 vaccine was significantly effective in both males and females.
The investigators found slightly more SARS-CoV-2 infections were recorded in females than in males, but the difference was not significant [RR = 1.064, 95% CI = 0.888 to 1.274, p = 0.502, I2 = 5.7%, p = 0.367].
The investigators concluded that despite significant biological and behavioral differences between males and females, there are no significant gender differences in the efficacy of the COVID-19 vaccines, especially in younger populations. Further pragmatic trials are needed to confirm the gender differences in protective response of different types of vaccines to different age groups.
Original title:
Is there a difference in the efficacy of COVID-19 vaccine in males and females? - A systematic review and meta-analysis by Zhu Z, Xu L and Chen G.
Link:
https://pubmed.ncbi.nlm.nih.gov/34623224/
Additional information of El Mondo:
Find more information/studies on coronavirus and vaccination right here.