Nutritional Advice El Mondo
Objectives:
Does vitamin D deficiency increase the risk of infection, severity and mortality of COVID-19?
Study design:
This review article included 23 eligible studies involving the relationship between vitamin D and Covid-19 infection/outcomes with a total of 206,861 participants.
3 meta-analyses have been carried out; called D-CIMA, D-CSMA and D-CMMA for Covid-19 infection, severity and mortality, respectively.
Results and conclusions:
The investigators found persons with a low serum vitamin D level had a significantly 1.64 times [95% CI = 1.32 to 2.04, p 0.001] higher chance to get COVID-19 infection.
The investigators found people with the serum 25(OH)D level below 20ng/mL or 50nmol/L had a significantly 2.58 times [95% CI = 1.28 to 5.19, p = 0.008] higher chance to get severe COVID-19.
The investigators found that low vitamin D level had no effect on COVID-19 mortality [OR = 2.42, 95% CI = 0.73 to 8.04, p = 0.148].
The investigators concluded that vitamin D deficiency increases the risk of COVID-19 infection and the severity of the disease. Therefore, vitamin D supplements should be added to prevention and treatment protocols for COVID-19 disease.
Original title:
The role of vitamin D deficiency on the Covid-19: A systematic review and meta-analysis of observational studies by Kaya MO, Pamukçu E and Yakar B.
Link:
https://pubmed.ncbi.nlm.nih.gov/34607398/
Additional information of El Mondo:
Find more information/studies on coronavirus and vitamin D right here.