Objectives:
While immunosuppression poses a theoretical increase in the risk of COVID-19, the nature of this relationship is yet to be ascertained. Therefore, this review article has been conducted.
Does immunosuppression therapy increase risk of COVID-19?
Study design:
This review article included 6 individual studies, contributing a total of 10,049 patients with COVID-19 disease.
Results and conclusions:
The investigators found the prevalence of immunosuppressed patients among the study cohorts with COVID-19 ranged from 0.126% to 1.357%.
The investigators found in the pooled cohort a total of 64/10,049 (0.637%) patients with COVID-19 disease was immunosuppressed.
The investigators found the observed to expected ratio of immunosuppression among patients with COVID-19 illness, relative to the general community, was 0.12 [95% = 0.05 to 0.27].
The investigators concluded compared to the general population, immunosuppressed patients are not at significantly increased risk of COVID-19 infection. This finding provides support for current expert consensus statements, which have recommended the continuation of immunosuppressant therapy in the absence of COVID-19.
Original title:
Immunosuppression as a risk factor for COVID-19: a meta-analysis by Tassone D, Thompson A, […], Ding NS.
Link:
https://pubmed.ncbi.nlm.nih.gov/33631862/
Additional information of El Mondo:
Find more information/studies on coronavirus right here.