Infection risk of COVID-19 of household contacts is 10 times higher than other contacts

Objectives:
What is the rate of transmission of COVID-19 within households?

Study design:
This review article included 10 retrospective cohort studies, 1 prospective study and 13 case ascertainment studies. Most studies (19/24) were conducted in China, with 2 in South Korea, 2 in the USA and 1 in Germany.
All the studies were conducted between Jan 1 and March 31, 2020.

Results and conclusions:   
The investigators found meta-analysis showed the risk of household transmission in adults was about 3-times higher than that in children [OR = 3.67, 95% CI = 2.76 to 4.87, p 0.001].

The investigators found meta-analysis showed the risk of household transmission was about 10 times higher than that from other contacts [OR = 10.72, 95% CI = 5.70 to 20.17, p 0.001].

The investigators found SARS-CoV-2 (COVID-19) was much more transmissible than SARS-CoV and Middle East Respiratory Syndrome Coronavirus in households.

The investigators concluded infection risk of COVID-19 of household contacts is 10 times higher than other contacts. Risk of household transmission in adults is about 3-times higher than that in children. Furthermore, SARS-CoV-2 (COVID-19) is much more transmissible than SARS-CoV and Middle East Respiratory Syndrome Coronavirus in households, which challenges the home isolation of COVID-19 patients.

Original title:
Household transmission of COVID-19-a systematic review and meta-analysis by Lei H , Xu X, […], Shu Y.

Link:
https://www.journalofinfection.com/article/S0163-4453(20)30571-5/fulltext

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