Nutritional Advice El MondoObjectives:
Is diabetes mellitus associated with severe infection and mortality in patients with COVID-19?
Study design:
This review article included 76 studies, involving 31,067 patients with COVID-19.
The number of confirmed COVID-19 cases in each study ranged from 41 to 3,841.
The proportion of diabetic patients ranged from 3.3 to 68.5%.
There was no statistically publication bias.
Results and conclusions:
The investigators found COVID-19 patients with diabetes mellitus had higher severe infection and case-mortality rates compared with those without diabetes mellitus [21.4 vs. 10.6% and 28.5 vs. 13.3%, respectively, all p 0.01].
The investigators found COVID-19 patients with diabetes mellitus were at significantly elevated risk of severe infection [OR = 2.38, 95% CI = 2.05 to 2.78, p 0.001, I2 = 39%, p 0.01] and mortality [OR = 2.21, 95% CI = 1.83 to 2.66, p 0.001, I2 = 50%, p 0.01].
The results remained similar for subgroup analysis.
The investigators concluded diabetes mellitus is associated with increased risk of severe infection and higher mortality in patients with COVID-19. These findings suggest that clinicians should pay more attention to the monitoring and treatment of COVID-19 patients with diabetes mellitus.
Original title:
Diabetes Mellitus is Associated with Severe Infection and Mortality in Patients with COVID-19: A Systematic Review and Meta-analysis by Shang L, Shao M, […], Tang B.
Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7413048/
Additional information of El Mondo:
Find more information/studies on diabetes mellitus and coronavirus right here.