Nutritional Advice El Mondo
Objectives:
There have been no published systematic reviews that combine clinical, laboratory, epidemiologic and mortality findings. Also, the effect of gender on the outcomes of COVID-19 has not been well-defined. Therefore, this review article has been conducted.
What are the clinical, laboratory, epidemiologic and mortality findings and the effect of gender on the outcomes of COVID-19?
Study design:
This review article included 34 studies with a total of 5,057 COVID-19 patients with a mean age of 49 years.
Results and conclusions:
The investigators found fever [83.0%, 95% CI = 77.5% to 87.6%] and cough [65.2%, 95% CI = 58.6% to 71.2%] were the most common symptoms.
The investigators found the most prevalent comorbidities were hypertension [18.5%, 95% CI = 12.7% to 24.4%] and cardiovascular disease [14.9%, 95% CI = 6.0% to 23.8%].
The investigators found among the laboratory abnormalities, elevated C-Reactive Protein (CRP) [72.0%, 95% CI = 54.3 to 84.6] and lymphopenia [50.1%, 95% CI = 38.0% to 62.4%] were the most common.
The investigators found bilateral ground-glass opacities [66.0%, 95% CI = 51.1% to 78.0%] was the most common CT scan presentation.
The investigators found the pooled mortality rate was 6.6%, with males having significantly higher mortality compared to females [OR = 3.4, 95% CI = 1.2 to 9.1, p = 0.01].
The investigators concluded the mortality is significantly higher among the hospitalized male group. However, further studies are required to evaluate the effect of different variables resulting in sex disparity in COVID-19 mortality.
Original title:
COVID-19 Clinical Characteristics, and Sex-Specific Risk of Mortality: Systematic Review and Meta-Analysis by Nasiri MJ, Haddadi S, […], Mirsaeidi M.
Link:
https://pubmed.ncbi.nlm.nih.gov/32793620/
Additional information of El Mondo:
Find more information/studies on coronavirus right here.