There is a wide spectrum of cardiac involvement in COVID-19 patients

Objectives:
Coronavirus disease 2019 (COVID-19) pandemic has drastically affected global health. Despite several studies, there is yet a dearth of data regarding the mechanisms of cardiac injury, clinical presentation, risk factors and treatment of COVID-19-associated cardiovascular disease. Therefore, this review article has been conducted.

Does cardiovascular disease increase risk of COVID-19?

Study design:
This review article included 35 studies.

Results and conclusions:   
The investigators found acute cardiac injury occurred in more than 25% of cases, mortality was 20 times higher and admission to intensive care unit increased by 13.5 times.

The investigators found hypertension was the most common pre-existing comorbidity with a frequency of 29.2%, followed by diabetes mellitus (13.5%).

The investigators found the deceased group of patients had higher cardiac and inflammatory biomarkers, with statistically significant SMD, compared with survivors.

The investigators found pediatric patients were predominantly mildly affected. However, less frequently, the presentation was very similar to Kawasaki disease or Kawasaki shock syndrome. This latter presentation has been called as multisystem inflammatory syndrome in children (MIS-C).

The investigators concluded there is a wide spectrum of cardiac involvement in COVID-19 patients and hence a Triage Risk Stratification Tool can serve as a guide for the timely recognition of the high-risk patients and mechanism-targeted therapy.

Original title:
Cardiovascular disease in COVID-19: a systematic review and meta-analysis of 10,898 patients and proposal of a triage risk stratification tool by Momtazmanesh S, Shobeiri P, […], Rad EM.

Link:
https://pubmed.ncbi.nlm.nih.gov/32661796/

Additional information of El Mondo:
Find more information/studies on coronavirus right here.