Nutritional Advice El Mondo
Objectives:
Does flaxseed supplementation decrease plasma lipoprotein(a) levels?
Study design:
This review article included 7 RCTs with 629 individuals.
Results and conclusions:
The investigators found flaxseed supplementation significantly reduced plasma lipoprotein(a) levels [MD = -2.06 mg/dL, 95% CI = -3.846 to -0.274, p = 0.024, I2 = 0%, p = 0.986].
The investigators found subgroup analysis also revealed that longer duration only showed significant lowering effect of flaxseed supplementation on plasma lipoprotein(a) levels.
The investigators concluded that long duration of flaxseed supplementation decreases plasma lipoprotein(a) levels. However, future well-designed and long-term clinical trials are required to confirm these results.
Original title:
Impact of flaxseed supplementation on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled trials by Hadi A, Askarpour M, […], Ghavami A.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/32073724
Additional information of El Mondo:
Find here more information/studies about flaxseed and heart disease.
Lipoprotein(a) is a risk factor for atherosclerosis and related diseases, such as coronary heart disease and stroke.