Nutritional Advice El Mondo
Objectives:
Are growth parameters at birth associated with maternal urinary iodine concentration (UIC) or normal ranges of thyroid hormones during pregnancy?
Study design:
This review article included 11 studies.
The pooled mean birth weight, length and head circumference values and 95% confidence intervals were estimated in newborns born to women with UIC 150 μg/L and UIC ≥150 μg/L during pregnancy.
Results and conclusions:
The investigators found pooled mean birth weight, length and head circumference in newborns whose mothers had UIC 150 μg/L vs UIC ≥150 μg/L were 2,898g vs 2,900g [p = 0.970], 49.6 cm vs 49.4 cm [p = 0.880] and 34.0 cm vs 34.1 cm [p = 0.933], respectively.
The investigators found dose-response meta-analyses revealed no significant linear or nonlinear associations between maternal urinary iodine concentration during pregnancy and anthropometric measures at birth.
The investigators found high vs normal values of maternal free thyroxine and thyrotropin during pregnancy were inversely associated with neonatal birth weight.
The investigators concluded that birth weight is affected by even mild variations in the normal concentrations of maternal thyroid hormones. However, in the current meta-analysis, birth anthropometric measures are not associated with maternal urinary iodine concentration during pregnancy.
Original title:
Do maternal urinary iodine concentration or thyroid hormones within the normal range during pregnancy affect growth parameters at birth? A systematic review and meta-analysis by Nazeri P, Shab-Bidar S, […], Shariat M.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/31923312
Additional information of El Mondo:
Find more information/studies on food fortification/malnutrition and pregnancy right here.