Nutritional Advice El Mondo
Objectives:
Human papillomavirus (HPV) vaccination has been proven to effectively protect against HPV infection and infection-associated cancer. However, there are concerns about the relationship between HPV vaccination and the risk of autoimmune disorders (ADs). Therefore, this review article has been conducted.
Does human papillomavirus vaccination increase risk of autoimmune disorders?
Study design:
This review article included in total 12 cohort studies, 6 case-control studies and 2 randomized controlled trials (RCTs) involving more than 169,000 autoimmune disorders events.
Results and conclusions:
The investigators found that human papillomavirus vaccination was not associated with an increased risk of subsequent autoimmune disorders [OR = 1.003, 95% CI = 0.95-1.06],
Most of the subgroup analysis results based on the location or type of autoimmune disorders were consistent with the overall results.
The investigators found, however, that human papillomavirus vaccination significantly reduced risk of autoimmune disorders with 18% [OR = 0.82, 95% CI = 0.7-0.96] among those with prior autoimmune disorders.
The investigators concluded that human papillomavirus vaccination is not associated with an increased risk of autoimmune disorders. However, given the low number of estimates for individual autoimmune disorder, additional and larger observational studies are needed to verify these findings.
Original title:
Human papillomavirus vaccination and the risk of autoimmune disorders: A systematic review and meta-analysis by Jiang HY, Shi YD, […], Ruan B.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/31036452
Additional information of El Mondo:
Find more information/studies on food fortification/malnutrition and vaccination right here.