Nutritional Advice El MondoObjectives:
Meta-analyses on the effect of vitamin D intake on status in children are lacking, especially those focused on vitamin D-fortified foods. Therefore, this review article has been conducted.
What is the effect of vitamin D interventions (fortified foods, supplements, bolus injections) on vitamin D status in children 2-18 y of age?
Study design:
This review article included 26 RCTs (5,403 children) with interventions (n = 9 fortified foods, n = 15 supplements, n = 2 bolus injections) from 100-4,000 IU vitamin D/d over 4 wk to 2 y.
Results and conclusions:
The investigators found the serum 25-hydroxyvitamin D weighted mean difference for all 26 trials [WMD = 23.5 nmol/L, 95% CI = 20.7 to 26.3 nmol/L, I2 = 99.9%] resulted in a mean increase of 1.0 nmol/L [95% CI = 0.3 to 1.7 nmol/]) for each increase of 100 IU vitamin D/d [per 1 µg/d: 0.4 nmol/L, 95% CI = 0.1 to 0.7 nmol/L].
The investigators found the response per 100 IU vitamin D/d was greater in trials with a mean baseline serum 25-hydroxyvitamin D 30 nmol/L, with the use of fortified foods and with baseline (=at the beginning of the study) vitamin D intakes 100 IU/d.
The investigators concluded the serum 25-hydroxyvitamin D response to vitamin D intake differs on the basis of baseline status, intakes and delivery mode, but not age, sex or latitude in children 2-18 y of age.
Original title:
Effect of Vitamin D Supplementation, Food Fortification, or Bolus Injection on Vitamin D Status in Children Aged 2-18 Years: A Meta-Analysis by Brett NR, Gharibeh N and Weiler HA.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/30032221
Additional information of El Mondo:
Find more information/studies on food fortification/malnutrition and vitamin D right here.
It is not possible to get 100 IU vitamin D through food items. It is only possible through supplementation.