Objectives:
The relationships between metabolic syndrome (MetS) and risk of incident stroke are inconsistent. Therefore, this review article (meta-analysis) has been conducted.
Does metabolic syndrome increase risk of stroke?
Study design:
This review article included a total of 16 prospective cohort studies, including 116,496 participants who were initially free of cardiovascular diseases.
Results and conclusions:
The investigators found comparing the persons without metabolic syndrome, those with metabolic syndrome had a significantly higher risk of 70% for incident stroke [pooled relative risk (RR) = 1.70, 95% CI = 1.49-1.95]. Significant means that there is an association with a 95% confidence.
The investigators found in subgroup analyses that women with metabolic syndrome had a significantly higher risk of 83% for incident stroke [pooled relative risk (RR) = 1.83, 95% CI = 1.31-2.56]. Significant because RR of 1 was not found in the 95% CI of 1.31 to 2.56. RR of 1 means no risk/association.
The investigators found in subgroup analyses that men with metabolic syndrome had a significantly higher risk of 47% for incident stroke [pooled relative risk (RR) = 1.47, 95% CI = 1.22-1.78].
The investigators found in subgroup analyses that those with metabolic syndrome had a significantly higher risk of 112% for ischemic stroke [pooled relative risk (RR) = 2.12, 95% CI = 1.46-3.08].
The investigators found in subgroup analyses that those with metabolic syndrome had a non-significantly higher risk of 48% for hemorrhagic stroke [pooled relative risk (RR) = 1.48, 95% CI = 0.98-2.24].
The investigators concluded metabolic syndrome increases risk of stroke, particularly among women and those with ischemic stroke.
Original title:
Metabolic syndrome and stroke: A meta-analysis of prospective cohort studies by Li X, Li X, […], Gao Q.
Link:
http://www.sciencedirect.com/science/article/pii/S0967586816311079
Additional information of El Mondo:
Find more information/studies on overweight and cardiovascular disease right here.
Find out whether you are overweight or not right here.
Those with metabolic syndrome are advised to select the following food items.