Nutritional Advice El Mondo
Objectives:
Thyroid cancer (TC) is the most common malignancy of the endocrine system. The relationship between iodine intake and thyroid cancer risk is controversial always. Therefore, this review article (meta-analysis) has been conducted.
Does dietary intake of iodine reduce thyroid cancer risk?
Study design:
This review article included 8 case-control studies with in total 2213 subjects with thyroid cancer and 2761 subjects without thyroid cancer.
With regard to publication bias, owing to the limited number (below 10) of studies included in the saltwater fish, shellfish and iodine intake analyses, publication bias was not assessed.
Results and conclusions:
The investigators found adequate or excess iodine dietary intake (>300 μg/d) significantly decreased the risk of thyroid cancer with 26% [OR = 0.74, 95% CI = 0.60-0.92].
The investigators found high consumption of saltwater fish (≥3 times/wk or ≥12 times/mo) significantly decreased the risk of thyroid cancer with 28% [OR = 0.72, 95% CI = 0.55-0.95, p = 0.02].
The investigators found high consumption of shellfish (≥3 times/wk or ≥12 times/mo) significantly decreased the risk of thyroid cancer with 30% [OR = 0.70, 95% CI = 0.52-0.96, p = 0.03].
The investigators concluded a higher intake of dietary iodine (>300 μg/d) may decrease the risk of thyroid cancer in populations mainly based in coastal cities or on islands. May decrease, because this review article did not include cohort studies.
Original title:
The relationship between iodine intake and the risk of thyroid cancer: A meta-analysis by Cao LZ, Peng XD, [...], Li S.
Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440127/
Additional information of El Mondo:
Find more information/studies on iodine and fish consumption, meta-analysis/cohort studies and cancer right here.