Objectives:
Recent studies have found that the serum zinc levels were associated with the risk of Parkinson's disease (PD), but the results were inconsistent. Therefore, this meta-analysis (review article) has been conducted.
Is there an association between serum zinc levels and Parkinson's disease risk?
Study design:
This review article included 11 articles involving 822 Parkinson's disease patients and 777 healthy controls (subjects without Parkinson's disease).
No publication bias was found.
Results and conclusions:
The investigators found that the serum zinc levels in Parkinson's disease patients were significantly lower than those in health controls [SMD = -0.779, 95% CI = -1.323 to -0.234, p 0.001].
This association was also significant in oriental studies [SMD = -1.601, 95% CI = -2.398 to -0.805, p 0.001].
The investigators concluded that serum zinc levels in Parkinson's disease patients are significantly lower than those in healthy controls.
Original title:
Association Between Serum Zinc Levels and the Risk of Parkinson's Disease: a Meta-Analysis by Sun H, Liu X, […], Li W.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/28160244
Additional information of El Mondo:
Find more information/studies on zinc right here.