Quarantined households will be a significant venue for transmission of COVID-19

Objectives:
What is the role of quarantined households for transmission of COVID-19?

Study design:
This review article included a total of 54 relevant studies with 77,758 participants reporting household secondary transmission.

Results and conclusions:                
The investigators found that the estimated household secondary attack rate was 16.6% [95% CI = 14.0% to 19.3%], higher than secondary attack rates for SARS-CoV [7.5%, 95% CI = 4.8% to 10.7%] and MERS-CoV [4.7%, 95% CI = 0.9% to 10.7%].

The investigators found household secondary attack rates were increased from:
-symptomatic index cases [18.0%, 95% CI = 14.2% to 22.1%] than from asymptomatic index cases [0.7%, 95% CI = 0% to 4.9%];
-to adult contacts [28.3%, 95% CI = 20.2% to 37.1%] than to child contacts [16.8%, 95% CI = 12.3% to 21.7%];
-to spouses [37.8%, 95% CI = 25.8% to 50.5%] than to other family contacts [17.8%, 95% CI = 11.7% to 24.8%] and;
-in households with 1 contact [41.5%, 95% CI = 31.7% to 51.7%] than in households with 3 or more contacts [22.8%, 95% CI = 13.6% to 33.5%].

The investigators concluded that given that individuals with suspected or confirmed infections are being referred to isolate at home, households will continue to be a significant venue for transmission of SARS-CoV-2 (COVID-19).

Original title:
Household Transmission of SARS-CoV-2: A Systematic Review and Meta-analysis by Madewell ZJ, Yang Y, […], Dean NE.

Link:
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2774102

Additional information of El Mondo:
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