Nutritional Advice El MondoObjectives:
Clinical trials examining the cardiovascular protective effects of quercetin in humans have reported conflicting results. Therefore, this review article has been conducted.
Do quercetin supplements reduce plasma lipid levels and blood pressure?
Study design:
This review article included 17 RCTs with a total of 896 participants.
Results and conclusions:
The investigators found pooled results showed that quercetin supplements significantly lowered both systolic blood pressure [WMD = -3.09 mmHg, 95% CI = -4.59 to -1.59, p = 0.0001] and diastolic blood pressure [WMD = -2.86 mmHg, 95% CI = -5.09 to -0.63, p = 0.01].
Neither lipid profiles nor glucose concentrations changed significantly.
The investigators found in subgroup analyses, significant changes in high-density lipoprotein (HDL or good) cholesterol and triglycerides were observed in trials with a parallel design and in which participants consumed quercetin for 8 weeks or more.
The investigators concluded quercetin supplements decrease blood pressure in humans. Moreover, participants who consume quercetin for 8 weeks or more show significantly changed levels of high-density lipoprotein cholesterol (good cholesterol) and triglycerides in trials with a parallel design.
Original title:
Effect of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels: a systematic review and meta-analysis by Huang H, Liao D, [...], Pu R.
Link:
https://www.ncbi.nlm.nih.gov/pubmed/31940027
Additional information of El Mondo:
Find more information/studies on lowering of cholesterol level and blood pressure and cardiovascular disease right here.