Severity of COVID-19 is associated with liver damage

Objectives:
Is the severity of COVID-19 associated with liver damage?

Study design:
This review article included 8 articles comprising 7,467 COVID-19 patients.

Results and conclusions:   
The investigators found when compared between severe and non-severe COVID-19 patients, the pooled ORs of elevated alanine aminotransferase, aspartate aminotransferase, total bilirubin and lactate dehydrogenase levels were 2.35 [95% CI = 1.38 to 3.98], 3.21 [95% CI = 2.59 to 3.98], 1.87 (95% CI = 1.32 to 2.65] and 4.83 [95% CI = 2.90 to 8.05], respectively.

The investigators concluded the severity of COVID-19 is associated with liver damage and can be a risk factor for abnormal liver function tests.

Original title:
Abnormal Liver Function Tests of Patients With Coronavirus Disease 2019 in Mainland China: A Systematic Review and Meta- Analysis by Xin S, Xu J and Yu Y.

Link:
https://pubmed.ncbi.nlm.nih.gov/32530989/?from_term=meta-analysis+and+covid+19&from_sort=date&from_pos=1

Additional information of El Mondo:
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