Troponin I >13.75 ng/L combined with >60 years is the best model to predict poor outcomes of COVID-19

Afbeelding

Objectives:
Is there an association between COVID-19 severity and mortality rate with the history of cardiovascular diseases and/or other comorbidities and cardiac injury laboratory markers?   

Study design:
This review article included 56 studies with 17,794 COVID-19 patients.

Results and conclusions:   
The investigators found COVID-19 patients with high cardiac troponin I [OR = 5.22, 95% CI = 3.73 to 7.31, p 0.001] and AST levels [OR = 3.64, 95% CI = 2.84 to 4.66, p 0.001] were more likely to develop adverse outcomes.

The investigators concluded high troponin I >13.75 ng/L combined with either advanced age >60 years or elevated AST level >27.72 U/L is the best model to predict poor outcomes of COVID-19.

Original title:
Association of Cardiac Biomarkers and Comorbidities With Increased Mortality, Severity, and Cardiac Injury in COVID-19 Patients: A Meta-Regression and Decision Tree Analysis by Toraih EA, Elshazli RM, […], Fawzy MS.

Link:
https://pubmed.ncbi.nlm.nih.gov/32530509/?from_term=meta-analysis+and+covid+19&from_sort=date&from_pos=2

Additional information of El Mondo:
Find more information/studies on coronavirus and cardiovascular diseases right here.