Vitamin D deficiency increases severity of COVID-19

Objectives:
There is still limited evidence regarding the influence of vitamin D in people with COVID-19. Therefore, this review article has been conducted.

Does vitamin D deficiency increase risk of COVID-19 infections?

Study design:
This review article included 27 articles.

Results and conclusions:   
The investigators found vitamin D deficiency was not associated with a higher chance of infection by COVID-19 [OR = 1.35, 95% CI = 0.80 to 1.88].  

The investigators found that severe cases of COVID-19 present 64% [OR = 1.64, 95% CI = 1.30 to 2.09] more vitamin D deficiency compared with mild cases.

The investigators found a vitamin D concentration insufficiency significantly increased hospitalization with 81% [OR = 1.81, 95% CI = 1.41 to 2.21] and mortality from COVID-19 with 82% [OR = 1.82, 95% CI = 1.06 to 2.58].

The investigators concluded that there is a positive association between vitamin D deficiency and the severity of COVID-19.

Original title:
Vitamin D deficiency aggravates COVID-19: systematic review and meta-analysis by Pereira M, Damascena  AD, […], da Mota Santana J.

Link:
https://pubmed.ncbi.nlm.nih.gov/33146028/

Additional information of El Mondo:
Find more information/studies on coronavirus and vitamin D right here.