13 gram soja-eiwit verhoogt overlevingskansen onder borskankerpatiënten

Research Question:
Information about the associations between the consumption of soy and the survival rates of breast cancer are contradictory. It was therefore carried out this review article.

Eating soy lowers the chances of survival for breast cancer patients?

Study Design:
This overview article contained 5 cohort studies with 11206 breast cancer patients. The average follow-up period was 3.9 to 7.3 years. 

Results and conclusions:
The researchers found that eating soy mortality among breast cancer patients significantly with 15% [95% CI = 0.77-0.93, I2 = 20%] reduced. Significant is, there is a link at a 95% reliability.

The researchers found that eating soy the relapse of breast cancer significantly with 21% [95% CI = 0.72-0.87, I2 = 0%] reduced.

The researchers found that the daily food of 2.12-7.03 grams of soy protein compared with less than 2.12 grams per day, the mortality among breast cancer patients significantly with 27% [95% CI = 0.54-0.98] reduced. Significant is, there is a link at a 95% reliability.

The researchers found that eating more than the 13.03 grams daily soy protein compared with less than 2.12 grams per day, the mortality among breast cancer patients significantly with 29% [95% CI = 0.52-0.98] reduced.

The researchers found that the daily food of 7.03-13.03 grams of soy protein compared with less than 2.12 grams per day, the mortality among breast cancer patients not significant with 29% [95% CI = 0.44-1.15] reduced. Not significant is, there is no link to a 95% reliability.

The researchers found that the daily food of more than 10 mg soy isoflavones compared with less than 4 grams per day, the relapse of breast cancer significantly with 26% [95% CI = 0.59-0.92] reduced.

The researchers found in subgroup analyses (to get more information) that eating soy mortality among THERE negative breast cancer significantly with 22% [95% CI = 0.70-0.85] reduced.

The researchers found that eating soy in subgroup analyses the positive breast cancer mortality among significantly with 25% [95% CI = 0.69-0.84] reduced.

The researchers found that eating soy in subgroups analyses the relapse of breast cancer under there +/PR + patients significantly with 30% [95% CI = 0.60-0.80] reduced.

The researchers found that eating soy the relapse of breast cancer among patients who used tamoxifen, not significant 17% [95% CI = 0.92-1.47, I2 = 0%] increased

The researchers found that eating soy in subgroup analyses the mortality among postmenopausal breast cancer patients significantly with 25% [95% CI = 0.67-0.84, I2 = 36%] reduced but not under Premenopausal Breast cancer patients [HR = 0.92, 95% CI = 0.78-1.08, I2 = 0%].

The researchers concluded that eating more than 13 grams of soy protein a day, the mortality (death to) under borskankerpatiënten reduced and more than 10 mg of soy isoflavones per day reduced the relapse of breast cancer. Further increased eating soy the relapse of breast cancer among patients taking tamoxifen, not used.

Original title:
Post diagnosis soy food intake and breast cancer survival: a meta-analysis of cohort studies by Chi F, Wu R, [...], Xu ZG.

Link:
http://www.apocpcontrol.org/paper_file/issue_abs/Volume14_No4/%202407-12%203.11%20Feng%20Chi.pdf

Additional information about El Mondo:

Products

Total soy isoflavones (mg)

Daidzein (mg)

Genistein (mg)

Soy beans (100 g)

128.34

46.46

73.76

Natto (100 grams)

58.93

21.85

29.04

Fried tofu (100 grams)

48.35

17.83

28

Tempeh (100 grams)

43.52

17.59

24.85

Soft tofu (100 grams)

29.24

8.59

20.65

Miso (100 grams)

42.55

 

 

Miso soup (100 grams)

60.39

 

 

Soy protein isolate (100 grams)

97.43

 

 

100 grams of soy beans delivers about 35 grams of protein.

This meal delivers 35 mg soy isoflavones.